Product Description
RENODAPT contains Mycophenolate Mofetil which belongs to the class of medicines called ‘immunosuppressants’. It is used to prevent the body from rejecting a transplanted organ such as a kidney, heart or liver. Transplant rejection occurs when the recipient’s immune system identifies the transplanted organ as a ‘foreign object’ and attacks it. If it is not treated promptly, it may cause irreversible damage. RENODAPT Tablet may be given in combination with other immunity suppressing medicines for effective results.
It is an immunosuppressive medicine, works by inhibiting the enzyme inosine -5′-monophosphate dehydrogenase (IMPDH) and reducing the production of guanosine nucleotides preferentially in T and B lymphocytes, thereby suppressing cell-mediated immune responses and antibody formation.
Inform the doctor If you have any infection or symptoms of infections, unexpected bruising or bleeding, lung or breathing problems, stomach ulcer, liver problems, ulcers in your stomach or intestines, HIV, neurogenetic disorder, hepatitis B or C (or if you are a carrier of the virus), cancer, if you have received or are scheduled to receive any vaccines.
Inform the doctor about all your medical conditions, prescription and non-prescription drugs, vitamin supplements, herbal medications, since RENODAPT can interact with them. RENODAPT can cause an allergic reaction in some patients therefore it is necessary to read the complete composition list and consult the doctor in case of any ingredient that induces allergies.
Consult the doctor if you are planning, on a pregnancy or breastfeeding.
It is advisable to avoid driving and operating heavy machinery during the course of RENODAPT.
RENODAPT may make your skin more sensitive to sun, so it is better to use sunscreen and protective clothing when outdoors.
Indications of RENODAPT
RENODAPT is used to prevent the body from rejecting a transplanted organ such as a kidney, heart or liver.
Therapeutic Effects of RENODAPT
It is an immunosuppressive medicine, works by inhibiting the enzyme inosine -5′-monophosphate dehydrogenase (IMPDH) and reducing the production of guanosine nucleotides preferentially in T and B lymphocytes, thereby suppressing cell-mediated immune responses and antibody formation. These effects suppress the immune system so that the transplanted graft is not rejected.
Directions for Use
RENODAPT should be taken with food preferably at the same time each day. The Tablet or capsule should be swallowed whole with water and should not be crushed, chewed, or opened. It is available as a dry powder and mixed with the liquid (mostly boiled and cooled water) up to the mark. Shake the bottle well before each use and take the dose as prescribed.
The dosage and duration of treatment will depend on the individual’s condition and response to the medication and should be determined by the doctor.
Your doctor will decide the dose and frequency of administration based on your health condition.
Storage
RENODAPT should be stored below 30°C temperature at room temperature. Do not freeze.
Keep in the original container to protect from light and moisture.
Keep RENODAPT out of sight and reach of children.
If you are traveling, carefully follow all patient instructions for storing your medicine during travel. Avoid extreme heat or cold.
Common:
- Nausea
- Vomiting
- Diarrhea
- Abdominal Pain
- Headache
- Nausea
- Dizziness
- High blood pressure
- Anaemia
- Rash
- Risk of developing lymphoma and other cancers
Serious:
- Heart problems (Irregular heartbeats, Heart failure such as rapid breathing, pedal edema, tachypnea)
- Infections, fever, cough
- Severe allergic reactions
- Unusual bleeding or bruising
- Low white blood cell (WBC) count
- Red blood cell (RBC) count
Tell a doctor or nurse straight away, if you notice any of the side effects above.
Contraindications
RENODAPT is contraindicated in patients with a known hypersensitivity to RENODAPT or any of the excipients.
Drug Interactions
RENODAPT might interact with other medicines. Therefore, it is recommended to inform your doctor about all the prescriptions you have.
Safety Advices of RENODAPT
Consult Your Doctor
Avoid alcohol consumption while taking RENODAPT as it may worsen the condition by increasing the risk of side-effects. Consult your doctor if you have history of Alcohol intake.Consult Your Doctor
RENODAPT is not recommended for use during pregnancy. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking RENODAPT. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Consult Your Doctor
It is not known whether RENODAPT passes into breast milk. Consult your doctor if you are breastfeeding before taking this medication.
Unsafe
RENODAPT may cause dizziness, tremor, low blood pressure, numb or confusion and vision disturbances in some patients. Therefore, avoid driving or operating machines that require mental concentration until you are not alert.
Consult Your Doctor
If you have any lung-related symptoms, consult your doctor before taking this medicine. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Consult Your Doctor
If you have any liver-related symptoms, consult your doctor before taking this medicine. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Consult Your Doctor
If you have any kidney-related symptoms, consult your doctor before taking this medicine. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Consult Your Doctor
RENODAPT should be used with caution in patients’ heart diseases. Consult your doctor before taking this medicine.
Unsafe
RENODAPT should be used with caution in children below 12 years of age. Your doctor may adjust the dose of this medicine based on your condition.
- 1. KD Tripathi. Immunosuppressant Drugs. Essentials of Medical Pharmacology. Seventh Edition,2013. Page - 883.
- 2. Jeffrey J Swigris, Amy L Olson, Aryeh Fischer, David A Lynch, Gregory P Cosgrove, Stephen K Frankel, Richard T Meehan, Kevin K Brown. Uses of Mycophenolate mofetil. National Institute of Health. NLM. National Centre for Biotechnology Information. Pubmed.gov. 2006. [Accessed on 16th July 2022] https://pubmed.ncbi.nlm.nih.gov/16840379/
- 3. Genentech USA, Inc., [ Revised on Oct 2021] [ Accessed on 25/05/2023], https://www.gene.com/download/pdf/RENODAPT_prescribing.pdf
- 4. Biocon. Mycophenolate mofetil. [Accessed on 16th July 2022] https://www.biocon.com/docs/prescribing_information/nephrology/renodapts540_pi.pd
- 5. Central Drugs Standard Control Organisation. Mycophenolate mofetil. [Accessed 25 Jul. 2023] (online) Available from: https://cdscoonline.gov.in/CDSCO/Drugs

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Renodapt 500mg | Renodapt 500mg |
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