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Product Description
SCAPHO INJECTION contains Secukinumab which belongs to the group of medicines called monoclonal antibodies. It is used to treat moderate to severe plaque psoriasis, active psoriatic arthritis (PsA), active ankylosing spondylitis (AS), active non-radiographic axial spondyloarthritis (nr-axSpA).
It is an immunosuppressive medicine, works by inhibiting the release of inflammatory cytokines and chemokines that contribute to autoimmune and inflammatory diseases.
Inform the doctor If you have or have ever had Tuberculosis or any active infection, lung or breathing problems, heart problems, kidney problems, liver problems, skin problems, ulcers in your stomach or intestines, nervous system disorders, diabetes, HIV, cancer, if you have received or are scheduled to receive any vaccines.
Inform the doctor about all your medical conditions, prescription and non-prescription drugs, vitamin supplements, herbal medications, since SCAPHO can interact with them. SCAPHO can cause an allergic reaction in some patients therefore it is necessary to read the complete composition list and consult the doctor in case of any ingredient that induces allergies.
Consult the doctor if you are planning, on a pregnancy or breastfeeding. It is advisable to avoid driving and operating heavy machinery during the course of SCAPHO.
Indications of SCAPHO Injection
SCAPHO is primarily indicated for the treatment of moderate to severe plaque psoriasis in patients six years and older who are candidates for systemic therapy or phototherapy, active psoriatic arthritis (PsA) in patients two years and older; adults with active ankylosing spondylitis (AS), adults with active non-radiographic axial spondyloarthritis (nr-axSpA).
TherapeuticEffects of SCAPHO Injection
It is an immunosuppressive medicine, works by blocking the action of inflammatory protein interleukin-17 (IL-17) receptor in the body that are responsible for causing inflammation and manage symptoms of psoriasis, hidradenitis suppurativa, psoriatic arthritis and axial spondyloarthritis.
Directions for Use
SCAPHO can be administered either as an injection under the skin, preferably at same time every day. The dosage and duration of treatment will depend on the individual’s condition and response to the medication and should be determined by the doctor.
Your doctor will decide the dose and frequency of administration based on your health condition.
A trained healthcare doctor/Nurse will administer SCAPHO. So, do not self-administer.
Storage
SCAPHO Injection should be stored in refrigerator at 2°C to 8°C. Do not freeze. Do not shake.
If you are traveling, carefully follow all patient instructions for storing your medicine during travel. Avoid extreme heat or cold.
Keep in the original container to protect from light and moisture.
Keep SCAPHO Injection out of sight and reach of children.
Common:
- Mild nose and throat infection
- Upper respiratory tract infection
- Diarrhea
- Headache
- Nausea
- Tiredness
Serious:
- Injection site reactions
- Inflammatory bowel disease
- Infections
Tell a doctor or nurse straight away, if you notice any of the side effects above.
Contraindications
SCAPHO Injection is contraindicated in patients with a known hypersensitivity to SCAPHO or any of the excipients.
Drug Interactions
SCAPHO might interact with other medicines. Therefore, it is recommended to inform your doctor about all the medications and supplements you take.
Safety Advices for Spegra Tablet
Consult Your Doctor
It is not known whether SCAPHO Injection interacts with alcohol. However, it is best to avoid alcohol or limit your alcohol consumption while taking any medication. Consult your doctor if you have history of Alcohol intake.
Unsafe
SCAPHO Injection is not recommended for use in pregnancy. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking SCAPHO Injection.
Consult Your Doctor
It is not known whether SCAPHO passes into breast milk. Consult your doctor if you are breastfeeding before taking this medication.
Unsafe
SCAPHO may cause weakness and tiredness in some patients. Therefore, avoid driving or operating machines that require mental concentration until you are not alert.
Consult Your Doctor
If you have any lung-related symptoms, consult your doctor before taking this medicine. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Consult Your Doctor
If you have a pre-existing or a history of liver problems, consult your doctor before taking this medicine. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Consult Your Doctor
If you have a pre-existing or a history of kidney disease, inform your doctor. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Unsafe
SCAPHO may be used in children with 2 years and older. Your doctor may adjust the dose of this medicine based on your age and condition.
- 1. Secukinumab [FDA Label]. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2015 [Accessed 20 Jan. 2020] (online) Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/125504s000lbl.pdf
- 2. Drugs.com. Secukinumab Pregnancy and Breastfeeding Warnings. [Accessed 20 Jan. 2020] (online) Available from: https://www.drugs.com/pregnancy/secukinumab.html
- 3. Ahmed A. Negm, & Daniel E. Furst, NSAIDs, Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 642-666.
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