- Your cart is empty
- Continue Shopping
Product Description
Tecentriq is an anti-cancer medicine that contains the active substance atezolizumab. It is used for the treatment of locally advanced or metastatic urothelial carcinoma, for the treatment of metastatic non-small cell lung cancer (NSCLC), for the treatment of advanced triple negative breast cancer (TNBC), hepatocellular carcinoma (HCC), and melanoma (a type of skin cancer). It belongs to a group of medicines called monoclonal antibodies. They are specialized proteins designed to recognize and attach to specific targets in the body. These antibodies can assist your immune system in fighting cancer.
Inform the doctor If you have or have ever had an organ or bone marrow transplant or radiation therapy to your chest area; lung or breathing problems; any condition that affects your nervous system, an autoimmune disease, ulcerative colitis, lupus, diabetes; thyroid problems; or kidney or liver disease.
Inform the doctor about all your medical conditions, prescription and non-prescription drugs, vitamin supplements, herbal medications, since Tecentriq can interact with them. Tecentriq can cause an allergic reaction in some patients therefore it is necessary to read the complete composition list and consult the doctor in case of any ingredient that induces allergies.
Consult the doctor if you are planning, on a pregnancy or breastfeeding.
It is advisable to avoid driving and operating heavy machinery during the course of Tecentriq.
Indications of TECENTRIQ Injection
Tecentriq indicated for the treatment of locally advanced or metastatic urothelial carcinoma (a type of bladder cancer), for the treatment of metastatic non-small cell lung cancer (NSCLC), for the treatment of advanced triple negative breast cancer (TNBC), hepatocellular carcinoma (HCC), and melanoma (a type of skin cancer).
Therapeutic Effects of TECENTRIQ Injection
Tecentriq Injection contains Atezolizumab, a type of immunotherapy drug falls under the class of monoclonal antibodies. It works by blocking the protein, called programmed death-ligand 1 (PD-L1) , which is present on certain tumor cells, from binding to another protein called PD-1 on immune cells. By binding to PD-L1 and inhibiting its interactions with both PD-1 and B7.1 receptors, Tecentriq enables immune cells to target and combat tumors.
Directions for Use
Tecentriq is usually given as an intravenous infusion over 60 minutes once every 3 weeks. This medication may be used in combination with other chemotherapy medications. The dosage and duration of treatment will depend on the individual’s condition and response to the medication and should be determined by the doctor.
Your doctor will decide the dose and frequency of administration based on your health condition.
A trained healthcare doctor/Nurse will administer Tecentriq. So, do not self-administer.
Storage
Tecentriq Injection should be stored in refrigerator at 2°C to 8°C. Do not freeze. Do not shake.
If you are traveling, carefully follow all patient instructions for storing your medicine during travel. Avoid extreme heat or cold.
Keep in the original container to protect from light and moisture.
Keep Tecentriq Injection out of sight and reach of children.
Common:
- Poor appetite
- Headache
- Nausea
- Fatigue
- Constipation
- Common Cold
- Fever
- Hair loss
- Rash
- Dry and itchy skin
- Nail problems
- Heartburn
- Breathlessness
- Feeling dizzy
- Pain in the joints, muscles, and bones
Serious:
- Severe or persistent diarrhea
- Low red blood cell count
- Hypersensitivity
- Infusion reactions with symptoms that can either be mild or more severe and may include feeling sick (nausea), fever, chills, feeling tired, headache, loss of appetite, joint and muscle pains.
- Allergic and anaphylactic (more severe allergic) reactions with symptoms that may include swelling of your face and throat, with difficulty in breathing.
- Inflammation (brain, heart muscle, kidney, muscle, lung, liver, intestine, thyroid, adrenal glands, and pituitary gland)
- Symptoms may include kidney problem, heart problems (fluttering of the heart at a faster or slower heartbeat, shortness of breath; and sudden dizziness), seizures, vomiting or diarrhoea and tingling in the mouth, hands or feet.
- Eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights.
Tell a doctor or nurse straight away, if you notice any of the side effects above.
Contraindications
Tecentriq Injection is contraindicated in patients with a known hypersensitivity to Tecentriq or any of the excipients.
Drug Interactions
Tecentriq might interact with other medicines. Therefore, it is recommended to inform your doctor about all the prescriptions you have.
Safety Advices for TECENTRIQ Tablet
Consult Your Doctor
It is unknown whether Tecentriq Injection interacts with alcohol. Consult your doctor.
Unsafe
Tecentriq Injection is not recommended for use in pregnancy as it may harm your fetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Tecentriq Injection. Using effective birth control methods while on treatment is suggested.
Unsafe
It is not known whether Tecentriq passes into breast milk. Consult your doctor if you are breastfeeding before taking this medication.
Unsafe
Tecentriq may cause dizziness, lightheadedness, or fainting in some patients. Therefore, avoid driving or operating machines that require mental concentration until you are not alert.
Consult Your Doctor
If you have any lung-related symptoms, such as difficulty breathing, consult your doctor before taking Tecentriq, as this medication should be used with caution in such conditions. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Consult Your Doctor
If you have a pre-existing or a history of liver problems, consult your doctor before taking this medicine. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Consult Your Doctor
If you have a pre-existing or a history of kidney disease, inform your doctor. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Unsafe
Tecentriq is not recommended for use in children as the safety and efficacy are not established.
FAQs
Ans – Tecentriq is an intravenous infusion used in the treatment of Lung Cancer, Breast Cancer, Liver Cancer, Skin Cancer, Bladder Cancer.
Ans – Tecentriq belongs to a class of immunotherapy drugs known as checkpoint inhibitors. It works by stimulating the body’s immune system to target and attack cancer cells.
Ans - Tecentriq (atezolizumab) was approved by:
-Food and Drugs Administration (FDA) (USA)
- Health Canada on April 12, 2017
- European Medicines Agency (EMA) (EU)
Ans - Avoid drinking alcohol during the treatment with Tecentriq even though no interactions of both are known.
Ans - It is advisable to avoid driving and operating heavy machinery as Tecentriq causes dizziness, lightheadedness, or fainting in some patients.
- 1. Roche, Electronic Medicines Compendium (EMC) [Revised on Feb 2022], [Accessed on 25th April 2023], Tecentriq 1,200 mg concentrate for solution for infusion - Patient Information Leaflet (PIL) - (emc) (medicines.org.uk)
- 2. Genentech Inc, US Food and Drug Administration [Revised on Oct 2021] [Accessed on 25th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/761034s028lbl.pdf
- 3. Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules, Goodman & Gilman's Pharmacological
Disclaimer
While we strive to provide complete, accurate, and expert-reviewed content on our ‘Platform’, we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user’s risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship. All Trademarks, Brands and Service marks that appear on this website belong to their respective owner.
