Product Description
VALCYTE contains the active substance Valganciclovir. It is used for the treatment of cytomegalovirus (CMV) infection of the retina of the eye in adult AIDS patients. It is also used to prevent CMV infection in patients who received an organ transplant from a donor infected with CMV.
Valganciclovir belongs to the medication group known as Antiviral (Non-HIV) drugs. It works by converting to ganciclovir in the body and inhibits the multiplication of the virus. Thereby, it helps to control the infection.
Inform the doctor if you have any active infection, low leucocyte count, low immune system, diarrhea, stomach pain, diabetes, kidney problems, or liver problems.
Inform the doctor about all your medical conditions, prescription and non-prescription drugs, vitamin supplements, and herbal medications, as VALCYTE can interact with them. VALCYTE can cause an allergic reaction in some patients therefore it is necessary to read the complete composition list and consult the doctor in case of any ingredient that induces allergies.
Consult the doctor if you are planning, on a pregnancy or breastfeeding.
It is advisable to avoid driving and operating heavy machinery during the course of VALCYTE.
Indications of VALCYTE Tablet
VALCYTE indicated for the treatment of cytomegalovirus (CMV) infection of the retina of the eye in adult AIDS patients. It is also used to prevent CMV infection in patients who received an organ transplant from a donor infected with CMV.
Therapeutic Effects of VALCYTE Tablet
VALCYTE 450mg tablet is an antiviral medication, works by getting converted to ganciclovir in the body and inhibits the multiplication of the virus. Thereby, it helps to control the infection.
Directions for Use
VALCYTE should be swallowed whole with water and should not be crushed, chewed or broken up. The medicine can be taken with or without food. Taking these
medicines regularly at the same time increases their effectiveness. A dose of this medicine should not be missed as it can affect your recovery. The dosage and duration of treatment will depend on the individual’s condition and response to the medication.
Your doctor will decide the dose and frequency of administration based on your health condition.
Storage
VALCYTE should be stored below 30°C temperature at room temperature. Do not freeze.
Avoid extreme heat or cold.
Keep the medicine in the original container to protect from light and moisture.
Keep VALCYTE out of sight and reach of children.
Common:
- Diarrhea
- Fever
- Nausea
- Headache
- Cough
- Loss of appetite
- Low blood cell counts
- Vomiting
- Difficulty in sleeoing
- Stomach Pain
Serious:
- Allergic reactions
- Low blood counts
- Retinal detachment: sudden changes in vision, floaters, flashes of light
- Blood and bone marrow problems
- Kidney injury: urinating less often than usual, swelling in your feet, ankles, or hands, unexplained weight gain
Tell a doctor or nurse straight away, if you notice any of the side effects above.
Safety Advices for VALCYTE Tablet
Consult Your Doctor
It is unknown whether VALCYTE interacts with alcohol. However, it is best to avoid alcohol or limit your alcohol consumption while taking any medication.
Unsafe
VALCYTE is not recommended for use in pregnancy as it may harm your fetus. If you are pregnant or planning to get pregnant during the treatment, please consult your doctor. Your doctor will prescribe any potential risks if the benefits are found to outweigh the risks.
Unsafe
Avoid breastfeeding your baby while on the treatment with VALCYTE as it may pass through breast milk. Consult your doctor if you are breastfeeding before taking this medication.
Unsafe
VALCYTE may cause dizziness, drowsiness, shakiness or confusion in some patients. Therefore, avoid driving or operating machines that require mental concentration until you are not alert
Consult Your Doctor
If you have pre-existing or a history of lung problems, consult your doctor before taking VALCYTE. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition
Consult Your Doctor
If you have a pre-existing or a history of liver problems, consult your doctor before taking VALCYTE. It should be used cautiously in liver disease patients. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Consult Your Doctor
If you have a pre-existing or a history of kidney disease, consult your doctor before taking VALCYTE as it should be used cautiously in patients with moderate to severe renal impairment. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Unsafe
VALCYTE is not recommended for use in children below 18 years old as the safety and efficacy are not established
- 1. KD Tripathi, Essentials of Medical Pharmacology, Antiviral drugs, 7th edition, 2013, 801.
- 2.. Raleigh A. Bowden, Per Ljungman, David R. Snydman. Cytomegalovirus infection after solid organ transplantation. Transplant Infections. Edition. 2012. Page – 341.
- 3. Roche Products Limited, Electronic medicines compendium (EMC), [ Revised on April 2022] [ Accessed on 11th May 2023], pil.13566.pdf (medicines.org.uk).
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4. Genentech USA, US Food and Drug Administration, [ Revised on Aug 2010]
[ Accessed on 11th May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021304s008,022257s003lbl.pdf.

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